High affinity nerve growth factor receptor

spinqualitylabelsall models Caption for this structure Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function High affinity nerve growth factor receptor (TrkA) is a tyrosine kinase receptor. TrkA ligand - nerve growth factor activates the receptor by stabilizing homodimer formation which initiates transautophosphorylation.

3D structures of high affinity nerve growth factor receptor

Updated on 26-December-2018

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• High affinity nerve growth factor receptor
  • 1he7 – hTrkAChoE 282-413 – human
    
  • 2n90 – hTrkAChoE transmembrane domain 410-447 – NMR
    
  • 4crp – hTrkAChoE nerve growth factor-binding domain (mutant) 36-383 – NMR
    
  • 4f0i, 4gt5 – hTrkAChoE kinase domain 498-796
    
• High affinity nerve growth factor receptor complex
  • 5kvt, 5wr7 – hTrkAChoE kinase domain 498-796 + anticancer drug
    
  • 4aoj, 4pmm, 4pmp, 4pms, 4pmt, 4yne, 4yps, 5h3q, 6dkb, 6dkg, 6dki, 6dkw – hTrkAChoE kinase domain + inhibitor
    
  • 5kmj, 5kmk, 5kml, 5kmm, 5kmn, 5kmo, 6d1y, 6d1z, 6d20, 5i8a, 5jfs, 5jfv, 5jfw, 5jfx, 5kmi, – hTrkAChoE catalytic+juxtamembrane domains 376-698 + inhibitor
    
  • 2ifg – hTrkAChoE nerve growth factor-binding domain + nerve growth factor
    

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