3nss | pdb_00003nss

The 2009 pandemic H1N1 neuraminidase N1 lacks the 150-cavity in its active sites

spinqualitylabelsall models 3nss, resolution 1.90Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3nss is a 2 chain structure with sequence from I09a0. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: ACT, CA, MAN, NAG Related: 3beq Gene: NA (I09A0) Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Publication Abstract from PubMed Influenza A virus neuraminidase can be classified into groups 1 and 2 on the basis of its primary structure. The main structural feature of group 1 neuraminidase is an extra cavity in the active site, the 150-cavity. Here we present the crystal structure of neuraminidase from the 2009 pandemic H1N1 influenza strain. In contrast to other characterized N1 neuraminidases, which are all members of group 1, 2009 H1N1 neuraminidase does not have a 150-cavity. The 2009 pandemic H1N1 neuraminidase N1 lacks the 150-cavity in its active site.,Li Q, Qi J, Zhang W, Vavricka CJ, Shi Y, Wei J, Feng E, Shen J, Chen J, Liu D, He J, Yan J, Liu H, Jiang H, Teng M, Li X, Gao GF Nat Struct Mol Biol. 2010 Oct;17(10):1266-8. Epub 2010 Sep 19. PMID:20852645 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. See Also Neuraminidase

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