HPPK 3D structures

3D structures of HPPK

Updated on 21-February-2019

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• HPPK
  • 1hka, 1eq0 – EcHPPK – Escherichia coli
    
  • 1g4c, 1im6, 1kbr, 1rtz, 1tmj, 3hcx, 3hsd, 3hsj, 3hsz, 3ili, 3ill, 3kue, 3kug – EcHPPK (mutant)
    
  • 2f63, 2f65 – EcHPPK - NMR
    
• HPPK binary complex
  • 1cbk – HPPK + dihydro-dimethyl-6-hydroxypterin – Haemophilus influenza
    
  • 1eqm – EcHPPK + ADP
    
  • 1ex8 – EcHPPK + adenosine-tetraphosphate-methyl-dihydropterin
    
  • 1rb0 – EcHPPK + 6-hydroxymethylpterin-diphosphate
    
  • 3hd1, 3hsg, 3ht0, 3ilj, 3kuh – EcHPPK (mutant) + methyleneadenosine-triphosphate
    
  • 3ud5, 3ude, 3udv, 4f7v – EcHPPK + inhibitor
    
  • 4pzv - HPPK/DHPS + inhibitor - Francisella tularensis
    
  • 3qbc – SaHPPK + inhibitor – Staphylococcus aureus
    
• HPPK ternary complex
  • 1ru2, 1tmm – EcHPPK (mutant) + methyleneadenosine-triphosphate + 6-hydroxymethylpterin
    
  • 1dy3 – EcHPPK (mutant) + ATP + pteridine derivative
    
  • 3ip0 – EcHPPK + methyleneadenosine-triphosphate + pteridine derivative
    
  • 1f9h, 1hq2, 1q0n, 1ru1, 3ilo – EcHPPK (mutant) + methyleneadenosine-triphosphate + pteridine derivative
    
  • 3hd2 – EcHPPK (mutant) + methyleneadenosine-triphosphate + pterine
    
  • 4m5g, 4m5h, 4m5i, 4m5j, 4m5k, 4m5l, 4m5m, 4m5n – EcHPPK + methyleneadenosine-triphosphate + inhibitor
    
  • 1rao – EcHPPK (mutant) + AMP + 6-hydroxymethylpterin-diphosphate
    
  • 5etl, 5etm, 5etn, 5eto, 5etp, 5etq, 5etr, 5ets, 5ett, 5etv - EcHPPK + AMPCPP + inhibitor
    
  • 4crj, 4cwb, 4cyu - SaHPPK + AMPCPP + inhibitor
    
  • 2qx0 – HPPK + methyleneadenosine-triphosphate + pteridine derivative – Yersinia pestis
    

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Michal Harel