6cl2 | pdb_00006cl2

Caspase-7 in complex with Ac-ATS009-KE

spinqualitylabelsall models 6cl2, resolution 2.35Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6cl2 is a 6 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. NonStd Res: 1MH, 1U8, ACE, PF5 Activity: Caspase-7, with EC number 3.4.22.60 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [CASP7_HUMAN] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression promotes programmed cell death.

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