Anti-silencing factor

spinqualitylabelsall models Structure of yeast anti-silencing factor complex with Br- ions (PDB entry 1roc) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function Anti-silencing factor (ASF) or histone chaperone assits in chromatin assembly and remodeling during replication, transcription activation and gene silencing. ASF cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly and with histone regulatory homolog A (HIRA) to promote replication-independent assembly. Structural highlights ASF has an 80 residue segment which binds RNA at the N-terminal and a C-terminal which is composed of 80% Ser and Arg. 3D structures of anti-silencing factor Anti-silencing factor 3D structures

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Michal Harel, Alexander Berchansky