6dev

Human caspase-6 E35K

spinqualitylabelsall models 6dev, resolution 2.35Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6dev is a 4 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Activity: Caspase-6, with EC number 3.4.22.59 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [CASP6_HUMAN] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.

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