Azurin

spinqualitylabelsall models Structure of azurin containing Cu+2 ion (PDB code 1joi). Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function Azurin (AZ) is a blue copper protein. AZ mediates electron transfer and contains type I copper center. For details see Intramolecular Electron Transfer in Azurin. Relevance AZ was found to be a novel anticancer agent. Following the entry of the P. aeruginosa bacteria into human melanoma and breast cancer cells, the AZ complexes with the tumor suppressor p53. The complex stabilizes p53 and activates the apoptosis of the cancer cells. Structural highlights AZ active Cu binding site is shown here. 3D structures of azurin Azurin 3D structures

3D structures of azurin

Updated on 31-March-2019

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• Azurin
  • Intramolecular Electron Transfer in Azurin – PaAZ – Pseudomonas aeruginosa
    
• Cu+2 containing azurin
  • Azurin 3D structures, 1azr, 4azu, 5azu, 1azn, 1cc3, 1e5y, 1e5z, 1jze, 2ft6, 2ft7, 2ft8, 2fta, 3fs9, 3fsa, 3fsv, 3fsw, 3fsz, 3ft0, 5i26, 5i28, 5syd, 5yt7, 6gyi – PaAZ
    
  • 2azu, 3azu, 1ils, 1ilu, 2tsa, 2tsb, 1etj, 1ag0, 1ezl, 1jvo, 1gr7, 1xb3, 1xb6, 1xb8, 2ghz, 2hx7, 2oj1, 3in0, 3fpy, 3fq1, 3fq2, 3fqy, 3in2, 3jt2, 3jtb, 3np3, 3np4, 3oqr, 3n2j, 3u25, 4hhw, 4mfh, 4ko5, 4ko6, 4ko7, 4ko9, 4kob, 4koc, 4bww, 4hip, 4qkt, 4wkx – PaAZ (mutant)
    
  • 1cuo, 1uat – AZ – Methylomonas
    
  • 1joi – PfAZ – Pseudomonas fluorrescens
    
  • 1nwo – PpAZ – Pseudomonas putida
    
  • 1nwp – PpAZ + Zn+2
    
  • 2aza, 1azb, 1azc, 1rkr – AxAZ – Achromobacter xylosoxidans
    
  • 1dyz, 1dz0, 2ccw – AZ II – Alcaligenes xylosoxidans
    
  • 1jvl, 2idf – PaAZ (mutant) + Ni+2
    
  • 1uri, 1a4a, 1a4b, 1a4c – AdAZ (mutant)
    
  • 2h3x, 2h47, 2iaa – AZ + aromatic amine dehydrogenase – Alcaligenes faecalis
    
• Cu+2 containing lanthanide-modified azurin
  • 1bex, 1jzi, 1jze, 1jzf, 1jzj, 1jzh – PaAZ
    
  • 2i7s, 2fnw, 2i7o, 3ibo, 4hhg, 4k9j, 6mjr, 6mjs, 6mjt – PaAZ (mutant)
    
• Cu+1 containing azurin
  • 1jzg – PaAZ
    
  • 1r1c, 2gi0, 1i53, 2hx8, 2hx9, 2hxa, 2xv0, 2xv2, 2xv3 – PaAZ (mutant)
    
  • 2n0m – NgAZ residues 56-183 – Neisseria Gonorhoeae - NMR
    
• Other metals-containing azurin
  • 1aiz – AdAZ + Cd+2 – Achromobacter denitrificans
    
  • 1nzr – PaAZ (mutant) + Ni+2
    
  • 1vlx – PaAZ + Co+2
    
  • 1e67 – PaAZ + Zn+2
    
  • 2iwe – PaAZ (mutant) + Zn+2
    
  • 3uge – PaAZ + Ag+1
    
  • 4hz1 – PaAZ + Fe+2
    
  • 4qlw – PaAZ (mutant) + Fe+2
    
  • 4jkn – PaAZ + Hg+2
    
  • 3ay2 – NgAZ (mutant) + Zn+2
    

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