Bacteriorhodopsin

spinqualitylabelsall models Bacteriorhodopsin complex with retinal, 3han Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function Bacteriorhodopsin (Br) is a membrane protein in Archaea which moves protons across the cell membrane. See also Bacteriorhodopsin (Hebrew). Structural highlights Br is composed of 6 α-helical elements each containing a retinal molecule. The retinal changes its ground state conformation upon binding of a proton, causing the Br to change conformation to the activated state and pump the proton. The retinal interacts predominantly with hydrophobic and aromatic residues (Hydrophobic, Polar).

3D Structures of bacteriorhodopsin

Updated on 31-March-2019

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• Bacteriorhodopsin
  • Bacteriorhodopsin (Hebrew) - HsBr residues 163-231 – Halobacterium salinarum - NMR
    
  • 1bha, 1bhb - HsBr residues 1-71 - NMR
    
  • 1l0m– Br (mutant) – Halobacterium halobium – NMR
    
  • 4pxk - Br (mutant) – Haloarcula marismortui
    
  • 4qi1, 4qid, 5itc, 5ite, 5kkh – HwBr-I – Haloquadratum walsbyi
    
  • 4wav – HwBr-I (mutant)
    
  • 5azd – Br – Thermus thermophilus
    
• Bacteriorhodopsin complexes
  • 2ntu, 1py6, 1fbb, 1fbk, 1brx, 1ap9, 1at9, 5br2, 5br5 - HsBr + retinal
    
  • 1brd - HsBr + retinal – Cryo EM
    
  • 2wjk, 2wjl, 3vhz, 1s8l, 3t45 - HsBr (mutant) + lipid + retinal
    
  • 3han, 2hao, 3hap, 3haq, 3har, 3has, 3coc, 3cod, 1tn5, 1tn0, 1s51, 1s52, 1s53, 1s54, 1q5i, 1q5j, 1pxr, 1pxs, 3hao, 3utv, 3utw, 3utx, 3uty - HsBr (mutant) + retinal
    
  • 4md1, 4md2, 4ov0, 5vn7, 5vn9 - HsBr + lipid
    
  • 3ns0, 3nsb, 3mbv, 1x0s, 1x0i, 1x0k, 1xji, 1iw6, 4fpd, 2i1x, 1kme, 1qm8, 1bm1, 1brr, 2brd, 4hyx, 4xxj, 4y9h, 5a44, 5a45, 5b34, 5b35, 5b6v, 5b6w, 5b6x, 5b6y, 5b6z, 5h2h, 5h2i, 5h2j, 5h2k, 5h2l, 5h2m, 5h2n, 5h2o, 5h2p, 5j7a, 6g7h, 6g7i, 6g7j, 6g7k, 6g7l, 4x31, 4x32, 1c3w, 5zil, 5zim, 5zin – HsBr + lipid + retinal
    
  • 2at9 - HsBr + lipid + retinal – Cryo EM
    
  • 1s8j- HsBr (mutant) + lipid + NO3 + retinal
    
  • 1mgy - HsBr (mutant) + lipid + Br + retinal
    
  • 1qhj - HsBr + phytanyl derivavative + retinal
    
  • 4hwl – HsBr + heptane + hexane + retinal
    
  • 4hwl – HsBr + decane + hexane + tetradecane + octane + retinal
    
  • 1r84, 1r2n - HsBr + retinal – NMR
    
  • 1f50, 1c8r - HsBr-BR (mutant) + lipid + retinal
    
  • 1m0k, 1m0l, 1ixf, 2zfe- HsBr-K + lipid + retinal
    
  • 1e0p, 2ntw, 1vjm - HsBr-L + retinal
    
  • 1ucq, 1iw9, 1o0a – HsBr-L + lipid + retinal
    
  • 1kg8, 1kg9, 1kgb, 1dze, 1cwq, 2zzl, 2i20, 2i21, 1p8h, 1m0m - HsBr-M + lipid + retinal
    
  • 1f4z, 1c8s, 1p8i - HsBr-M (mutant) + lipid + retinal
    
  • 1p8u – HsBr-N (mutant) + lipid + retinal
    
  • 1jv6, 1jv7, 3vi0 - HsBr-O (mutant) + lipid + retinal
    
  • 1qko, 1qkp - HsBr + retinal
    
  • 5jsi – Br + lipid – Candidatus actinomarina
    
  • 5uk6 – Br + lipid – Nostoc - NMR
    
• Halorhodopsin
  • 3abw, 3a7k, 3vvk – NpBr+ N3 + bacterioruberin + detergent + retinal – Natronomonas pharaonis
    
  • 3qbg, 3qbi, 3qbk, 3qbl, 5etz - NpBr + bacterioruberin + detergent + retinal
    
  • 5b0w - NpBr + bacterioruberin + detergent + retinal + Ile
    
  • 4qry - NpBr + Br + detergent + retinal
    
  • 5ahy, 5ahz, 5g36 - HsBr + detergent + retinal
    
  • 2jaf, 2jag, 1e12 - HsBr (mutant) + lipid+ retinal
    
• Sensory rhodopsin II
  • 2ksy – NpBr – NMR
    
  • 2f93, 2f95, 1h2s - BpBr + Br transducer + detergent + retinal
    
  • 3qap, 3qdc - NpBr + eicosane + lipid + retinal
    
  • 4gyc, 5jje, 5jjf, 5jjj, 5jjn - NpBr + retinal + eicosane + lipid + Br transducer
    
  • 1gu8, 1gue, 1h68, 1jgj - NpBr + retinal
    
  • 1xio - AnBr + detergent + retinal - Anabaena
    
  • 4tl3 - AnBr (mutant) + detergent + retinal
    
  • 2m3g - AnBr + detergent - NMR
    
• Xanthorhodopsin
  • 3ddl – Br + detergent + salinixanthin + retinal – Salinibacter ruber
• Archaerhodopsin
  • 2ei4, 2z55 – HaBr + bacterioruberin + detergent + retinal – Halobacterium
    
  • 1vgo - HaBr + detergent + retinal
    
  • 1uaz - HaBr + retinal
    
• Blue-light absorbing proteorhodopsin
  • 4kly, 4knf - GpPRn + retinal
    
  • 4jq6 – PRn + retinal + lipid - uncultured bacteria
    
• Green-light absorbing proteorhodopsin
  • 2l6x - GpPRn + detergents + retinal – Gamma proteobacterium
    
  • 5abb – PRn residues 19-83 + protein translocase – Escherichia coli
    
• Deltarhodopsin
  • 4fbz - Rn + bacterioruberin + retinal – Haloterrigena thermotolerans
    
• Xenorhodopsin
  • 6eyu - Rn + eicosane + lipid + retinal – Nanosalina
    

See Also

• Rhodopsin
• G protein-coupled receptor

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Wayne Decatur, Jaime Prilusky, Joel L. Sussman