6d08 | pdb_00006d08
From Proteopedia
Crystal structure of an engineered bump-hole complex of mutant human chromobox homolog 1 (CBX1) with H3K9bn peptide
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Structural highlights
Function[CBX1_HUMAN] Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane. Contents | ||||||||||||||||||||
This page was last modified 07:09, 10 April 2019.