4mgu | pdb_00004mgu

Crystal structure of Acheta domesticus Densovirus

spinqualitylabelsall models 4mgu, resolution 3.50Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4mgu is a 2 chain structure with sequence from Acheta domestica densovirus and Acheta domesticus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Publication Abstract from PubMed The 3.5 A resolution X-ray crystal structure of mature cricket parvovirus (Acheta domesticus densovirus, AdDNV) has been determined. Structural comparisons show that vertebrate and invertebrate parvoviruses have evolved independently, although there are common structural features among all parvovirus capsid proteins. It was shown that raising the temperature of the AdDNV particles caused a loss of their genomes. The structure of these emptied particles was determined by cryo-electron microscopy to 5.5 A resolution and found to have the same capsid structure as the full, mature virus except for the absence of the three ordered nucleotides observed in the crystal structure. The viral protein 1 (VP1) amino termini could be externalized without significant damage to the capsid. In vitro, this externalization of the VP1 amino termini is accompanied by the release of the viral genome. The structure and host entry of an invertebrate parvovirus.,Meng G, Zhang X, Plevka P, Yu Q, Tijssen P, Rossmann MG J Virol. 2013 Sep 11. PMID:24027306 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

Proteopedia Page Contributors and Editors (what is this?)

OCA