5zrn | pdb_00005zrn

Inhibitor bound crystal structure of N-terminal domain of FACL13 from Mycobacterium tuberculosis

spinqualitylabelsall models 5zrn, resolution 2.37Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 5zrn is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: JSA Related: 3t5b Activity: Long-chain-fatty-acid--CoA ligase, with EC number 6.2.1.3 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [FAC13_MYCTO] Required for maintaining the appropriate mycolic acid composition and permeability of the envelope on its exposure to acidic pH. Catalyzes the activation of long-chain fatty acids as acyl-coenzyme A (acyl-CoA), which are then transferred to the multifunctional polyketide synthase (PKS) type III for further chain extension (By similarity).

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