6oe7 | pdb_00006oe7

Crystal structure of HMCES cross-linked to DNA abasic site

spinqualitylabelsall models 6oe7, resolution 2.20Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6oe7 is a 3 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: EDO, UNX NonStd Res: DRZ Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [HMCES_HUMAN] Specifically binds 5-hydroxymethylcytosine (5hmC)-containing DNA in stem cells, suggesting that it acts as a specific reader of 5hmC in stem cells (By similarity). May act as a peptidase; experimental evidences are however required to confirm this prediction (PubMed:23945014).

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