6o2x | pdb_00006o2x

Structure of cruzain bound to MMTS inhibitor

spinqualitylabelsall models 6o2x, resolution 1.19Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6o2x is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: EDO, PO4 NonStd Res: SCH Activity: Cruzipain, with EC number 3.4.22.51 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [CYSP_TRYCR] Hydrolyzes chromogenic peptides at the carboxyl Arg or Lys; requires at least one more amino acid, preferably Arg, Phe, Val or Leu, between the terminal Arg or Lys and the amino-blocking group. The cysteine protease may play an important role in the development and differentiation of the parasites at several stages of their life cycle.

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