4yjd | pdb_00004yjd

Crystal structure of DAAO(Y228L/R283G) variant (apo form)

spinqualitylabelsall models 4yjd, resolution 2.30Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4yjd is a 2 chain structure with sequence from Pig. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: FAD, SO4 Related: 4yjh, 4yjg, 4yjf Gene: DAO (PIG) Activity: D-amino-acid oxidase, with EC number 1.4.3.3 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [OXDA_PIG] Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids. See Also Amino acid oxidase 3D structures

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