4zv7 | pdb_00004zv7

Crystal structure of hexagonal form of lipase B from Candida antarctica

spinqualitylabelsall models 4zv7, resolution 2.00Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4zv7 is a 1 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: NAG Related: 1tca, 1tcb, 1tcc, 3w9b Activity: Triacylglycerol lipase, with EC number 3.1.1.3 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [LIPB_CANAR] Hydrolysis of triglycerides. Is very stereospecific both in hydrolysis and in organic synthesis and has a potentially important application in glucolipid synthesis. Publication Abstract from PubMed During crystallization screenings of commercially available hydrolytic enzymes, the new, hexagonal crystal form of CAL-B, has been discovered and hereby reported. The NAG molecules, which were closing the glycosylation site in the orthorhombic form, in hexagonal structure make the glycosylation site open. It is unknown whether the opening and closing of the glycosylation site by the 'lid' NAG molecules, could be related to the opening and closing of the active center of the enzyme upon substrate binding and product release. Crystal and molecular structure of hexagonal form of lipase B from Candida antarctica.,Strzelczyk P, Bujacz GD, Kielbasinski P, Blaszczyk J Acta Biochim Pol. 2015 Dec 30. PMID:26716135 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. See Also Lipase

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