5axd | pdb_00005axd

Crystal structure of mouse SAHH complexed with ribavirin

spinqualitylabelsall models 5axd, resolution 1.60Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 5axd is a 2 chain structure with sequence from Lk3 transgenic mice. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: NAD, RBV Related: 5axa, 5axb, 5axc Gene: Ahcy (LK3 transgenic mice) Activity: Adenosylhomocysteinase, with EC number 3.3.1.1 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [SAHH_MOUSE] Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine.

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