Structural highlights
6jxj is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Ligands: | ALF, CE1, CLR, MG, NAG, PCW, RB |
| Activity: | H(+)/K(+)-exchanging ATPase, with EC number 7.2.2.19 |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Disease
[ATP4B_PIG] Note=Parietal cell autoantigen associated with autoimmune gastritis.
Function
[ATP4A_PIG] Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach.
