6k01 | pdb_00006k01
From Proteopedia
Crystal structure of xH2A-H2B
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Structural highlights
Function[H2B11_XENLA] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Contents | ||||||||||||||||
This page was last modified 05:17, 10 October 2019.