6kku | pdb_00006kku

human KCC1 structure determined in NaCl and GDN

spinqualitylabelsall models 6kku, resolution 3.50Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6kku is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: BGC, CL, DU0, GLC, NAG Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [S12A4_HUMAN] Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May contribute to cell volume homeostasis in single cells. May be involved in the regulation of basolateral Cl(-) exit in NaCl absorbing epithelia (By similarity). Isoform 4 has no transport activity.

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