6ddi | pdb_00006ddi

Crystal Structure of the human BRD2 BD1 bromodomain in complex with a Tetrahydroquinoline analogue

spinqualitylabelsall models 6ddi, resolution 1.50Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6ddi is a 3 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: 03S, EDO, G7V, SO4 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [BRD2_HUMAN] May play a role in spermatogenesis or folliculogenesis (By similarity). Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly.

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