6s4n | pdb_00006s4n

LXRbeta ligand binding domain in comlpex with small molecule inhibitors

spinqualitylabelsall models 6s4n, resolution 1.90Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6s4n is a 4 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: KUW, SO4 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [NR1H2_HUMAN] Orphan receptor. Binds preferentially to double-stranded oligonucleotide direct repeats having the consensus half-site sequence 5'-AGGTCA-3' and 4-nt spacing (DR-4). Regulates cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8 (By similarity).

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