6o62 | pdb_00006o62

Crystal structure of Sec4p, a Rab family GTPase from Candida albicans

spinqualitylabelsall models 6o62, resolution 1.88Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6o62 is a 1 chain structure with sequence from Canal. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: GDP Gene: SEC4, CAALFM_CR01750CA, Ca49C4.03c, CaO19.10103, CaO19.2571 (CANAL) Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [SEC4_CANAL] Involved in exocytosis. Maybe by regulating the binding and fusion of secretory vesicles with the cell surface. The GTP-bound form of SEC4 may interact with an effector, thereby stimulating its activity and leading to exocytotic fusion. SEC4 may be an upstream activator of the 19.5S SEC8/SEC15 particle. SEC4 probably interacts directly with SEC8; it could serve as the attachment site for the SEC8/SEC15 particle (By similarity).

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