2y7j | pdb_00002y7j

Structure of human phosphorylase kinase, gamma 2

spinqualitylabelsall models 2y7j, resolution 2.50Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 2y7j is a 4 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: B49 Activity: Phosphorylase kinase, with EC number 2.7.11.19 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease [PHKG2_HUMAN] Glycogen storage disease due to liver phosphorylase kinase deficiency. The disease is caused by mutations affecting the gene represented in this entry. Function [PHKG2_HUMAN] Catalytic subunit of the phosphorylase b kinase (PHK), which mediates the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase. May regulate glycogeneolysis in the testis. In vitro, phosphorylates PYGM (By similarity).

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