6uuz | pdb_00006uuz

Structure of ACLY in the presence of citrate and CoA

spinqualitylabelsall models 6uuz, resolution 3.00Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6uuz is a 4 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: COA Activity: ATP citrate synthase, with EC number 2.3.3.8 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [ACLY_HUMAN] ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine.

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