6czc | pdb_00006czc

Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with thymidine triphosphate (TTP) - promiscuous binding mode with disordered nucleoside

spinqualitylabelsall models 6czc, resolution 2.30Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6czc is a 4 chain structure with sequence from Myctu. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: MG, TTP Related: 3fgn, 3fpa, 3fmi, 3fmf, 4wop, 6cve, 6cvf, 6cvu, 6cvv, 6czb, 6czd, 6cze Gene: bioD, Rv1570, MTCY336.33c (MYCTU) Activity: Dethiobiotin synthase, with EC number 6.3.3.3 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [BIOD_MYCTU] Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring. See Also Dethiobiotin synthetase 3D structures

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