6j7x | pdb_00006j7x

Complex of GGTaseIII, farnesyl-Ykt6, and GGPP

spinqualitylabelsall models 6j7x, resolution 2.75Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6j7x is a 3 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: FMT, GRG Gene: PTAR1 (HUMAN), RABGGTB, GGTB (HUMAN), YKT6 (HUMAN) Activity: Protein geranylgeranyltransferase type II, with EC number 2.5.1.60 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [YKT6_HUMAN] Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity. [PGTB2_HUMAN] Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX, such as RAB1A, RAB3A, RAB5A and RAB7A.

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