6k9q | pdb_00006k9q

Structure of the native supercoiled hook as a universal joint

spinqualitylabelsall models 6k9q, resolution 3.10Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6k9q is a 26 chain structure with sequence from Salmonella typhimurium. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Publication Abstract from PubMed The Bacterial flagellar hook is a short supercoiled tubular structure made from a helical assembly of the hook protein FlgE. The hook acts as a universal joint that connects the flagellar basal body and filament, and smoothly transmits torque generated by the rotary motor to the helical filament propeller. In peritrichously flagellated bacteria, the hook allows the filaments to form a bundle behind the cell for swimming, and for the bundle to fall apart for tumbling. Here we report a native supercoiled hook structure at 3.6 A resolution by cryoEM single particle image analysis of the polyhook. The atomic model built into the three-dimensional (3D) density map reveals the changes in subunit conformation and intersubunit interactions that occur upon compression and extension of the 11 protofilaments during their smoke ring-like rotation. These observations reveal how the hook functions as a dynamic molecular universal joint with high bending flexibility and twisting rigidity. Structure of the native supercoiled flagellar hook as a universal joint.,Kato T, Makino F, Miyata T, Horvath P, Namba K Nat Commun. 2019 Nov 22;10(1):5295. doi: 10.1038/s41467-019-13252-9. PMID:31757961 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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