Structural highlights
Function
[MGM1_YEAST] Dynamin-related GTPase required for mitochondrial fusion. Coordinates interaction between the inner and outer mitochondrial membrane to promote the formation of the double membrane.[1] [2] [3] [4]
References
- ↑ Shepard KA, Yaffe MP. The yeast dynamin-like protein, Mgm1p, functions on the mitochondrial outer membrane to mediate mitochondrial inheritance. J Cell Biol. 1999 Feb 22;144(4):711-20. doi: 10.1083/jcb.144.4.711. PMID:10037792 doi:https://dx.doi.org/10.1083/jcb.144.4.711
- ↑ Wong ED, Wagner JA, Scott SV, Okreglak V, Holewinske TJ, Cassidy-Stone A, Nunnari J. The intramitochondrial dynamin-related GTPase, Mgm1p, is a component of a protein complex that mediates mitochondrial fusion. J Cell Biol. 2003 Feb 3;160(3):303-11. PMID:12566426 doi:https://dx.doi.org/10.1083/jcb.200209015
- ↑ Herlan M, Vogel F, Bornhovd C, Neupert W, Reichert AS. Processing of Mgm1 by the rhomboid-type protease Pcp1 is required for maintenance of mitochondrial morphology and of mitochondrial DNA. J Biol Chem. 2003 Jul 25;278(30):27781-8. Epub 2003 Apr 21. PMID:12707284 doi:https://dx.doi.org/10.1074/jbc.M211311200
- ↑ Sesaki H, Jensen RE. Ugo1p links the Fzo1p and Mgm1p GTPases for mitochondrial fusion. J Biol Chem. 2004 Jul 2;279(27):28298-303. Epub 2004 Apr 14. PMID:15087460 doi:https://dx.doi.org/10.1074/jbc.M401363200
