6os1 | pdb_00006os1

Structure of synthetic nanobody-stabilized angiotensin II type 1 receptor bound to TRV023

spinqualitylabelsall models 6os1, resolution 2.79Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6os1 is a 3 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: CLR, OLC NonStd Res: SAR Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease [AGTR1_HUMAN] NON RARE IN EUROPE: Essential hypertension;Renal tubular dysgenesis of genetic origin. The disease is caused by mutations affecting the gene represented in this entry. Function [AGTR1_HUMAN] Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

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