Structural highlights
5bxt is a 2 chain structure with sequence from Bifidobacterium bifidum jcm 1254. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Ligands: | 4WS, GAL, SO4 |
| Related: | 5bxp, 5bxs, 5bxr |
| Gene: | lnbB (Bifidobacterium bifidum JCM 1254) |
| Activity: | Lacto-N-biosidase, with EC number 3.2.1.140 |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Publication Abstract from PubMed
The synthesis of potent inhibitors for lacto-N-biosidases and X-ray structural characterization of these compounds in complex with BbLNBase is described.
Gaining insight into the catalysis by GH20 lacto-N-biosidase using small molecule inhibitors and structural analysis.,Hattie M, Ito T, Debowski AW, Arakawa T, Katayama T, Yamamoto K, Fushinobu S, Stubbs KA Chem Commun (Camb). 2015 Aug 27. PMID:26312778[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
- ↑ Hattie M, Ito T, Debowski AW, Arakawa T, Katayama T, Yamamoto K, Fushinobu S, Stubbs KA. Gaining insight into the catalysis by GH20 lacto-N-biosidase using small molecule inhibitors and structural analysis. Chem Commun (Camb). 2015 Aug 27. PMID:26312778 doi:https://dx.doi.org/10.1039/c5cc05494j
