4pc4 | pdb_00004pc4

Bombyx mori lipoprotein 6

spinqualitylabelsall models 4pc4, resolution 1.80Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4pc4 is a 5 chain structure with sequence from Bombyx mori. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: EDO, IPA, MES, PEG Related: 3pub, 4efp, 4efq, 4efr, 4iy8, 4iy9 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Publication Abstract from PubMed The 30-kDa lipoprotein (LP) family of mulberry silkworm comprises major hemolymph proteins specific to the fifth instar larvae. The family consists of 46 members, 24 of which are referred to as typical 30-kDa LPs. To date, two crystal structures of 30-kDa LPs from Bombyx mori have been described (Bmlp3 and Bmlp7). Here, we present the crystal structure of Bmlp6, another 30-kDa LP member. Bmlp6 is comprised of two domains characteristic of this family, the VHS-type N-terminal domain and beta-trefoil C-terminal domain. The structures of the three 30-kDa LPs have been compared and a number of differences are noted, including loop conformation, the surface electrostatic potential, and the potential binding cavities. We discuss the observed structural differences in the light of the potential different roles of the particular 30-kDa LP members in silkworm physiology. Crystal structure of Bombyx mori lipoprotein 6: comparative structural analysis of the 30-kDa lipoprotein family.,Pietrzyk AJ, Bujacz A, Lochynska M, Jaskolski M, Bujacz G PLoS One. 2014 Nov 7;9(11):e108761. doi: 10.1371/journal.pone.0108761., eCollection 2014. PMID:25379889 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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