2f27 | pdb_00002f27

Crystal Structure of the Human Sialidase Neu2 E111Q-Q112E Double Mutant in Complex with DANA Inhibitor

spinqualitylabelsall models 2f27, resolution 2.15Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 2f27 is a 2 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: DAN, EPE Related: 1snt, 1so7, 1vcu, 2f0z, 2f10, 2f11, 2f12, 2f13, 2f24, 2f25, 2f26, 2f28, 2f29 Activity: Exo-alpha-sialidase, with EC number 3.2.1.18 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [NEUR2_HUMAN] Hydrolyzes sialylated compounds. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

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