5dxy | pdb_00005dxy

Crystal structure of Dbr2

spinqualitylabelsall models 5dxy, resolution 1.77Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 5dxy is a 1 chain structure with sequence from Artan. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: 5J8, FMN Related: 5dxx, 5dy2, 5dy3 Gene: DBR2 (ARTAN) Activity: Artemisinic aldehyde Delta(11(13)) reductase, with EC number 1.3.1.92 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [DBR2_ARTAN] Involved in the biosynthesis of the antimalarial endoperoxide artemisinin by catalyzing the double bond reduction of (11R)-dihydroartemisinic aldehyde to produce artemisinic aldehyde. Also able to reduce artemisinic alcohol and artemisinic acid to a lesser extent.

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