Nucleoside triphosphatase

spinqualitylabelsall models Caption for this structure Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function Nucleoside triphosphatase or nucleoside triphosphate diphosphohydrolase (NTPase) is responsible for degradation of nucleotides to their monophosphate form. NTPase is found in mammals and in pathogenic microbes. In mammals NTPase hs a crucial role in regulation of purinergic signalling by hydrolysis of extracellular nucleotides. The function of NTPase in pathogens is still unknown.

3D structures of nucleoside triphosphatase

Updated on 12-May-2020

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• Nucleoside triphosphatase 1
  • 4a57 - TgNTPase 1 - Toxoplasma gondii
    
  • 4a59 - TgNTPase 1 + AMP
    
• Nucleoside triphosphatase 2
  • 4jep - TgNTPase 2
    
  • 4a5b - TgNTPase 2 (mutant)
    
  • 4kh4, 4a5a - TgNTPase 2 (mutant) + AMPPNP
    
  • 4kh5, 4kh6 - TgNTPase 2 (mutant) + AMPNP
    
• Nucleoside triphosphatase Nudi
  • 6dt3 - Nudi - Klebsiella pneumoniae
    
  • 3oga, 3n77 - Nudi - Salmonella enterica
    
• Nucleoside triphosphatase cancer-related
  • 2i3b - NTPase - human- NMR
    
• Nucleoside triphosphatase
  • 3s86 - NTPase - Thermotoga maritima
    
  • 3agr - NTPase - Neospora caninum
    

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Michal Harel, Alexander Berchansky, Joel L. Sussman