Pdk1 3D structures

3D Structures of 3-phosphoinositide-dependent protein kinase 1

Updated on 25-May-2020

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• Pdk1 kinase domain 50-359
  • 1h1w – hPdk1 + PSer – human
    
  • 1uu3, 1uu7, 1uu8, 1uu9, 1uvr, 1z5m, 2pe0, 2pe1, 2pe2, 3h9o, 2xch, 2xck, 3qcq, 3qcs, 3qcx, 3qcy, 3qd0, 3qd3, 3qd4, 3nus, 3nuu, 3nuy, 3nun, 3sc1, 3rwp, 3rwq, 5hkm, 5hng, 5ho7, 5ho8 – hPdk1 + PSer + inhibitor
    
  • 3orx, 3orz, 3otu, 3qc4, 3rcj, 5lvl, 4xx9, 5ack – hPdk1 (mutant) + PSer + inhibitor
    
  • 2r7b, 3ion, 3iop, 3nax, 3nay – hPdk1 + inhibitor
    
  • 3pwy – hPdk1 (mutant) + inhibitor
    
  • 1oky, 1okz – hPdk1 + PSer + staurosporine
    
  • 2biy, 3hrc – hPdk1 (mutant) + ATP
    
  • 4ct1 – hPdk1 (mutant) + ATP + PSer + PS315
    
  • 5lvo – hPdk1 (mutant) + ATP + PSer + PSE10
    
  • 5lvp – hPdk1 (mutant) + ATP + PSer + peptide
    
  • 4ct2 – hPdk1 (mutant) + ATP + PSer
    
  • 5lvm – hPdk1 (mutant) + adenine + PSer
    
  • 5lvn – hPdk1 (mutant) + adenosine + PSer
    
  • 4rqk, 4rqv, 5mrd – hPdk1 (mutant) + ATP + PSer + inhibitor
    
  • 4rrv – hPdk1 (mutant) + ATP + PSer + serine/threonine protein kinase N2
    
  • 3hrf, 4a06, 4a07, 4aw0, 4aw1 – hPdk1 (mutant) + PSer + ATP + activator
    
• Pdk1 PH domain
  • 1w1h – hPdkl
    
  • 2vki – hPdk1 (mutant)
    
  • 1w1d, 1w1g – hPdk1 + inositol phosphate
    

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Michal Harel