2xo3 | pdb_00002xo3

Human Annexin V with incorporated Methionine analogue Homopropargylglycine

spinqualitylabelsall models 2xo3, resolution 2.30Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 2xo3 is a 1 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: CA, SO4 NonStd Res: IZO Related: 1hvg, 1hvd, 1avr, 1anw, 1avh, 1hak, 1hve, 1anx, 1hvf, 1sav, 2xo2 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease [ANXA5_HUMAN] Defects in ANXA5 are associated with susceptibility to pregnancy loss, recurrent, type 3 (RPRGL3) [MIM:614391]. A common complication of pregnancy, resulting in spontaneous abortion before the fetus has reached viability. The term includes all miscarriages from the time of conception until 24 weeks of gestation. Recurrent pregnancy loss is defined as 3 or more consecutive spontaneous abortions. Function [ANXA5_HUMAN] This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. See Also Annexin 3D structures

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