5nas | pdb_00005nas

Crystal structure of human 14-3-3 zeta in complex with PI4KIIIB peptide

spinqualitylabelsall models 5nas, resolution 2.08Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 5nas is a 4 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. NonStd Res: SEP Gene: YWHAZ (HUMAN) Activity: 1-phosphatidylinositol 4-kinase, with EC number 2.7.1.67 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [1433Z_HUMAN] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. [PI4KB_HUMAN] Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation. Involved in Golgi-to-plasma membrane trafficking (By similarity). See Also 14-3-3 protein 3D structures

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