NAD kinase

spinqualitylabelsall models NAD kinase complex with NADP and sulfate (PDB code 1z0u) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function NAD kinase (NADK) catalyzes the conversion of ATP and NAD to ADP and NADP. NADP is critical for metabolism, calcium signaling and anti-inflammatory processes. NADK is regulated by calmodulin-dependent mechanism. See NAD and NAD(P)H. Structural highlights NADP is bound to NADK in a cleft between the N and C-terminal domains in the dimer interface. Water molecules are shown as red spheres.

3D structures of NAD kinase

Updated on 09-September-2020

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• NAD kinase
  • NAD – NADK – human
    
  • NAD, NAD(P)H – MtNADK – Mycobacterium tuberculosis
    
  • 1y3h – MtNADK (mutant)
    
  • 1yt5 – NADK – Thermotoga maritima
    
  • 2i1w – LmNADK – Listeria monocytogenes
    
  • 5ejf, 5ejg, 5ejh – LmNADK (mutant)
    
  • 4hao – NADK – Yersinia pestis
    
  • 3pfn – NADK – human
    
• NAD kinase complex
  • 1y3i – MtNADK + NAD
    
  • 1z0s – AfNADK + ATP + PPi – Archaeoglobus fulgidus
    
  • 1z0u – AfNADK + NADP
    
  • 1z0z – AfNADK + NAD
    
  • 2i29 – LmNADK + NAD
    
  • 2i2a – LmNADK + NADP
    
  • 2i2b, 2i2c, 2i2d, 4dy6, 3v7u, 3v7w, 3v7y, 3v80, 3v8m, 3v7n, 3v7p, 5dhp, 5dhq, 5dhr, 5dhs, 5dht, 5dhu – LmNADK + adenosine derivative inhibitor
    
  • 2q5f, 3v8q, 3v8r – LmNADK (mutant) + adenosine derivative
    
  • 6rbo, 6rbp, 6rbq, 6rbr, 6rbs, 6rbt, 6rbu, 6rbv, 6rbw, 6rbx, 6rby, 6rbz, 6rc0, 6rc1, 6rc2, 6rc3, 6rc4, 6rc5, 6rc6, 6rr2 – LmNADK + adenine derivative
    
  • 6rg6, 6rg7, 6rg8, 6rg8, 6rg9, 6rga, 6rgb, 6rgc, 6rgd, 6rge, 6rgf – LmNADK + inhibitor
    
  • 2i2f – LmNADK (mutant) + NAD + Pi
    
  • 5eji – LmNADK (mutant) + NADP + PPi
    

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