Pyruvate kinase 3D structures

3D structures of pyruvate kinase

Updated on 20-October-2020

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• Pyruvate kinase
  • 3bjf, 3bjt, 1t5a, 1zjh, 3srf, 3srh - hPyK M1/M2 - human
    
  • 4wj8, 4qg6, 4qg8, 4qg9, 4qgc, 3g2g, 4yj5, 6b6u - hPyK M1/M2 (mutant)
    
  • 2vgb – hPyK LR
    
  • 6nn5, 6nn7, 6nn8, 2vgf, 2vgg, 2vgi – hPyK LR (mutant)
    
  • 1pkm, 1pyk – PyK – cat
    
  • 1f3w – rPyK – rabbit
    
  • 1f3x - rPyK (mutant)
    
  • 6du6 – PyK - mosquito
    
  • 1pky, 4yng, 6k0k – EcPyK - Eschericia coli
    
  • 1e0t, 1e0u - EcPyK (mutant)
    
  • 3t05, 3t0t – SaPyK – Staphylococcus aureus
    
  • 3qtg – PyK – Pyrobaculum aerophilum
    
  • 4krz - TcPyK – Trypanosoma cruzei
    
  • 5wrp - MtPyK – Mycobacterium tuberculosis
    
  • 3hqn, 3e0w, 1pkl – LmPyK – Leishmania mexicana
    
  • 3khd – PfPyK – Plasmodium falciparum
    
  • 3gg8, 3eoe – PyK – Toxoplasma gondii
    
  • 3ma8, 4drs – PyK – Cryptosporidium parvum
    
  • 2e28 - PyK (mutant) – Geobacillus stearothermophilus
    
• Pyruvate kinase binary complex
  • 4b2d - hPyK M1/M2 + fructose bisphosphate
    
  • 4rpp, 6nn4 - hPyK M2 (mutant) + fructose bisphosphate
    
  • 4fxj - hPyK M1/M2 + phenylalanine
    
  • 6gg3 - hPyK M2 + alanine
    
  • 6gg4 - hPyK M2 + phenylalanine
    
  • 6gg5 - hPyK M2 + tryptophan
    
  • 6gg6 - hPyK M2 + serine
    
  • 6nub - hPyK M2 (mutant) + serine
    
  • 6nu1 - hPyK M2 + cysteine
    
  • 6nu5 - hPyK M2 (mutant) + cysteine
    
  • 6ttf, 6tti, 6ttq - hPyK M2 + inhibitor – Cryo EM
    
  • 6tth - hPyK M2 + threonine – Cryo EM
    
  • 6v74, 6v75 - hPyK M2+ asparagine
    
  • 6v76 - hPyK M2 + valine
    
  • 6ech, 6eck - PyK PKLR + fructose bisphosphate - rat
    
  • 5x1v, 5x1w - hPyK M2 + inhibitor
    
  • 4rpp - hPyK M2 (mutant) + fructose bisphosphate
    **3qv9 – TcPyK + Ponceau S
    
  • 3qv6 – LmPyK + acid blue 80
    
  • 3e0v – LmPyK + sulfate
    
  • 3hqq - LmPyK + fructose bisphosphate
    
  • 3qv8 – LmPyK + benzothiazole
    
  • 3pp7 – LmPyK + suramin
    
  • 3is4, 3ktx – LmPyK + pyrenetetrasulfonic acid
    
  • 3t07 – SaPyK + bis-indole alkaloid
    
  • 4hyw – TbPyK + fructose bisphosphate – Trypanosoma brucei
    
  • 6su1, 6su2 – PyK + citrate – Trypanosoma congolense
    
  • 5ws8 - MtPyK + oxalate
    
  • 6p0y - CpPyK + ADP
    
• Pyruvate kinase higher complex
  • 3me3 – hPyK M1/M2 + aniline derivative + fructose bisphosphate
    
  • 4g1n - hPyK M1/M2 + pyridazine derivative + oxalate
    
  • 3h6o - hPyK M1/M2 + pyridazine derivative + fructose bisphosphate
    
  • 3gqy, 3gr4, 3u2z - hPyK M1/M2 + piperazine derivative + fructose bisphosphate
    
  • 5x0i - hPyK M2 (mutant) + serine + fructose bisphosphate
    
  • 6jfb - hPyK M2 + serine + phosphate
    
  • 5x1v, 5x1w - hPyK M2 + activator + fructose bisphosphate
    
  • 4jpg - hPyK M1/M2 + pyrimidine derivative + fructose bisphosphate
    
  • 3srd - hPyK M1/M2 + oxalate + fructose bisphosphate
    
  • 4fxf - hPyK M1/M2 + oxalate + ATP + fructose bisphosphate
    
  • 4ima, 4ip7 - hPyK L (mutant) + citrate + adenosine + fructose bisphosphate
    
  • 3n25 – rPyK M1/M2 + proline + Mn + pyruvate
    
  • 2g50 - rPyK M1/M2 + alanine + Mn + pyruvate
    
  • 1pkn - rPyK + Mn + pyruvate
    
  • 1aqf – rPyK + Mg + phospholactate
    
  • 1a49, 1a5u - rPyK + ATP + oxalate
    
  • 1a3w – yPyK + Mn + phosphoglycolic acid + fructose bisphosphate – yeast
    
  • 1a3x - yPyK + Mn + phosphoglycolic acid
    
  • 4hyv – TbPyK + phosphoenolpyruvate + fructose bisphosphate
    
  • 4kct – TbPyK + pyruvate + fructose bisphosphate
    
  • 4kcu – TbPyK + malate + fructose bisphosphate
    
  • 4kcv – TbPyK + oxoglutarate + fructose bisphosphate
    
  • 4kcw – TbPyK + oxalate + fructose bisphosphate
    
  • 4ks0 – TcPyK + oxalate + fructose bisphosphate
    
  • 5ws9 – MtPyK + oxalate + AMP + ATP
    
  • 5wsa – MtPyK + oxalate + glucose-6-phosphate
    
  • 5wsb, 5wsc – MtPyK + oxalate + glucose-6-phosphate + AMP
    
  • 6ito – MtPyK + oxalate + ribose-5-phosphate + AMP
    
  • 3hqo – LmPyK + ATP + oxalate
    
  • 3hqp - LmPyK + ATP + oxalate + fructose bisphosphate
    
  • 3qv7 – LmPyK + acid blue 25 + Ponceau S
    
  • 3srk – LmPyK + saccharine + inhibitor
    
  • 6qxl – PyK + malonate + glucose-6-phosphate + Mg – Pseudomonas aerugnosa
    
  • 6ksh – PfPyK + oxalate + ATP
    

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