3dax | pdb_00003dax

Crystal structure of human CYP7A1

spinqualitylabelsall models 3dax, resolution 2.15Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3dax is a 2 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: HEM, UNX Gene: CYP7A1, CYP7 (HUMAN) Activity: Cholesterol 7-alpha-monooxygenase, with EC number 1.14.13.17 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [CP7A1_HUMAN] Catalyzes a rate-limiting step in cholesterol catabolism and bile acid biosynthesis by introducing a hydrophilic moiety at position 7 of cholesterol. Important for cholesterol homeostasis. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also Cytochrome P450 3D structures

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