Reverse transcriptase 3D structures

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3D Structures of Reverse transcriptase

Updated on 22-October-2020

Italic text

    • 2jle – P66+NNRTI
    • 1har - P66 N-terminal
    • 5t82 - P66 thumb domain - NMR
  • Hiv-1 P15
    • 1rdh, 1hrh, 5dzm – P15
    • 3lp3 – P15+inhibitor MK3
    • 3k2p – P15+inhibitor beta-thujaplicinol
    • 3hyf – P15+pyrimidine derivative
    • 1o1w – P15+Mg - NMR
  • HIV-2 reverse transcriptase
  • Moloney murine leukemia virus reverse transcriptase
  • Xenotropic mulv-related virus reverse transcriptase
    • 3v1o, 3v1q – RNAse H domain
    • 3v1r – RNAse H domain + inhibitor
    • 4hkq – RT residues 658-1328 (mutant) + DNA + RNA
  • Telomerase reverse transcriptase see Telomerase
  • other RT
    • 4ol8 - P55 (mutant) + RNA + DNA - yeast
    • 6me0, 6mec - P55 + RNA + DNA – Thermosynechococcus elongatus – Cryo EM
    • 2lsn – RT – Simian foamy virus – NMR

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Michal Harel, Joel L. Sussman