Sandbox GGC12
Crystal Structure of Fab12
This is a default text for your page Sandbox GGC12. Click above on edit this page to modify. Be careful with the < and > signs. You may include any references to papers as in: the use of JSmol in Proteopedia [1] or to the article describing Jmol [2] [3] [4] to the rescue. FunctionControls the host immune response system against pathogens through recognition of molecular patterns specific to microorganism. TLR3 is a nuclear-sensing TLR which is going to be activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response. DiseaseA rare complication of human herpesvirus 1 (HHV-1) infection, occurring in only small minorities of HHV-1 infected individuals. It is characterized by hemorrhagic necrosis of parts of the temporal and frontal lobes. Onset is over several days and involves fear, headache, seizures, stupor, and often coma, frequently with a fatal outcome. RelevanceStructural highlightsThis is a sample scene created with SAT to color by Group, and another to make a transparent representation of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. This shows the secondary structure of Crystal Structure of Fab12. Here is a Zoomed in viewname='78/781196/Ser212/2'>Zoomed out view</scene>This is Ser212 which is important
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