1vb7 | pdb_00001vb7
From Proteopedia
Solution structure of the PDZ domain of PDZ and LIM domain 2
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Structural highlights
Function[PDLI2_MOUSE] Probable adapter protein located at the actin cytoskeleton that promotes cell attachment. Necessary for the migratory capacity of epithelial cells. Overexpression enhances cell adhesion to collagen and fibronectin and suppresses anchorage independent growth. May contribute to tumor cell migratory capacity (By similarity). Evolutionary Conservation![]() Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also | ||||||||||||||||||
This page was last modified 07:34, 30 December 2020.