Piezo proteins constitute a family of excitatory ion channels directly gated by mechanical forces. Piezo is functionally conserved and very important because all living organisms are subjected to mechanical forces from their environment for instance proprioception, osmoregulation, vascular tone, blood flow regulation, muscle homeostasie, flow sensing in kidney, bladder and lungs. [1],
[2]
Function
You may include any references to papers as in: the use of JSmol in Proteopedia [3] or to the article describing Jmol [4] to the rescue.
Structure
Disease
Relevance
Structural highlights
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- ↑ Zhao Q, Wu K, Geng J, Chi S, Wang Y, Zhi P, Zhang M, Xiao B. Ion Permeation and Mechanotransduction Mechanisms of Mechanosensitive Piezo Channels. Neuron. 2016 Mar 16;89(6):1248-1263. doi: 10.1016/j.neuron.2016.01.046. Epub 2016, Feb 25. PMID:26924440 doi:https://dx.doi.org/10.1016/j.neuron.2016.01.046
- ↑ Parpaite T, Coste B. Piezo channels. Curr Biol. 2017 Apr 3;27(7):R250-R252. doi: 10.1016/j.cub.2017.01.048. PMID:28376327 doi:https://dx.doi.org/10.1016/j.cub.2017.01.048
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:https://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
