2dv7 | pdb_00002dv7

Crystal structure of Lys187 to Arg mutant of Diphthine synthase

spinqualitylabelsall models 2dv7, resolution 2.30Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 2dv7 is a 2 chain structure with sequence from Pyrococcus horikoshii. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: GOL, MES, SAH, SO4 Related: 1wng, 2dv3, 2dv4, 2dv5 Gene: dphB (Pyrococcus horikoshii) Activity: Diphthine synthase, with EC number 2.1.1.98 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN Function [DPHB_PYRHO] S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also Diphthine synthase

Proteopedia Page Contributors and Editors (what is this?)

OCA