2ef1 | pdb_00002ef1

Crystal structure of the extracellular domain of human CD38

spinqualitylabelsall models 2ef1, resolution 2.40Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 2ef1 is a 2 chain structure with sequence from Human. This structure supersedes the now removed PDB entry 2df1. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: EPE Gene: CD38 (HUMAN) Activity: NAD(+) nucleosidase, with EC number 3.2.2.5 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN Function [CD38_HUMAN] Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also Cluster of Differentiation CD38

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