2fvz | pdb_00002fvz

Human Inositol Monophosphosphatase 2

spinqualitylabelsall models 2fvz, resolution 2.40Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 2fvz is a 4 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Gene: IMPA2, IMP.18P (HUMAN) Activity: Inositol-phosphate phosphatase, with EC number 3.1.3.25 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [IMPA2_HUMAN] Can use myo-inositol monophosphates, scylloinositol 1,4-diphosphate, glucose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. Has been implicated as the pharmacological target for lithium Li(+) action in brain. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also Inositol monophosphatase 3D structures

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