2fyp | pdb_00002fyp

GRP94 in complex with the novel HSP90 Inhibitor Radester amine

spinqualitylabelsall models 2fyp, resolution 1.95Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 2fyp is a 2 chain structure with sequence from Canlf. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: 1PE, PG4, RDE Related: 1zwh, 2fxs, 1qy8, 1u0z, 2exl, 1yet, 1bgq, 1osf Gene: TRA1 (CANLF) Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [ENPL_CANFA] Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity (By similarity). Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also Heat Shock Protein structures

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