6kqb | pdb_00006kqb

A long chain secondary alcohol dehydrogenase of Micrococcus luteus

spinqualitylabelsall models 6kqb, resolution 2.26Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6kqb is a 2 chain structure with sequence from "bacteridium_luteum"_schroeter_1872 "bacteridium luteum" schroeter 1872. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Related: 6kq9 Gene: GY12_10930 ("Bacteridium luteum" Schroeter 1872) Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Publication Abstract from PubMed Structure-based engineering of a NAD+-dependent secondary alcohol dehydrogenase from Micrococcus luteus led to a 1800-fold increase in catalytic efficiency for NADP+. Furthermore, the engineered enzymes (e.g., D37S/A38R/V39S/T15I) were successfully coupled to a NADPH-dependent Baeyer-Villiger monooxygenase from Pseudomonas putida KT2440 for redox-neutral biotransformations of C18 fatty acids into C9 chemicals. Cofactor specificity engineering of a long-chain secondary alcohol dehydrogenase from Micrococcus luteus for redox-neutral biotransformation of fatty acids.,Seo EJ, Kim HJ, Kim MJ, Kim JS, Park JB Chem Commun (Camb). 2019 Nov 28;55(96):14462-14465. doi: 10.1039/c9cc06447h. PMID:31728457 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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