2i7q | pdb_00002i7q

Crystal structure of Human Choline Kinase A

spinqualitylabelsall models 2i7q, resolution 1.90Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 2i7q is a 1 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: CL, UNX Gene: CHKA, CHK, CKI (HUMAN) Activity: Choline kinase, with EC number 2.7.1.32 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [CHKA_HUMAN] Has a key role in phospholipid biosynthesis and may contribute to tumor cell growth. Catalyzes the first step in phosphatidylcholine biosynthesis. Contributes to phosphatidylethanolamine biosynthesis. Phosphorylates choline and ethanolamine. Has higher activity with choline. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also Choline kinase 3D structures

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